Fertility Decoded

ICSI (intracytoplasmic sperm injection)

Injecting a single sperm directly into an egg. An established technique, not on HFEA's add-on list.

Established step

This is an established, standard technique used in specific situations — not a limited-evidence add-on.

The verdict

Needed for male-factor infertility; not a general upgrade for everyone.

Evidence positions on ICSI (intracytoplasmic sperm injection) from HFEA, ESHRE, NICE and ISAR
BodyPosition
HFEA
  • Not on HFEA's rated listfor chance of a baby
ESHREIndicated for male factor

Indicated for male-factor infertility; no benefit for routine ICSI in non-male-factor patients, and it adds cost.

Source
NICEOffer for male factor

Recommended for male-factor infertility (see NG257 ICSI section).

Source
ISARIndicated cases only

Should be used judiciously in indicated cases only.

Source

In India

Additional cost ~₹15,000–45,000 over conventional IVF.

Sources

Take this further

Last reviewed .