Fertility Decoded

IMSI (high-magnification sperm selection)

Selecting sperm under very high magnification before ICSI.

The verdict

Not shown to improve outcomes.

Evidence positions on IMSI (high-magnification sperm selection) from HFEA, ESHRE, NICE and ISAR
BodyPosition
HFEA
  • Grey — insufficient evidencefor chance of a baby
ESHRENot for routine use

Not recommended for routine clinical use.

Source
NICENot addressed

Not addressed in NG257.

ISARNeeds robust RCTs

Need robust RCTs to suggest use; very low-quality evidence in support.

Source

In India

Charged as an advanced-lab add-on, ~₹15,000–40,000 (varies; often bundled).

Sources

Take this further

Last reviewed .