Fertility Decoded

MACS / microfluidics sperm sorting

Newer ways to select 'better' sperm — magnetically (MACS) or by swim-through chips (microfluidics/Zymot).

The verdict

Limited evidence — microfluidics may be considered; MACS not routine.

Evidence positions on MACS / microfluidics sperm sorting from HFEA, ESHRE, NICE and ISAR
BodyPosition
HFEA
  • Not on HFEA's rated listfor chance of a baby
ESHREMicrofluidics: can be considered; MACS: not routine

Microfluidics can be considered (single Fertile-Chip RCT); MACS not recommended for routine clinical use.

Source
NICENot addressed

Not addressed in NG257.

ISARData collection advised

Data collection recommended; not enough robust data to recommend routine use.

Source

In India

Sperm-prep add-on, ~₹5,000–20,000; approximate.

Sources

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